An Overview on Bioinformatics and its Application
DOI:
https://doi.org/10.37591/(rrjobi).v3i2.399Abstract
Bioinformatics has become an important part of many areas of biology. The term ‘Bioinformatics’ was coined by Paulien Hogeweg in 1979. In experimental molecular biology, bioinformatics techniques such as image and signal processing allow extraction of useful results from large amounts of raw data. In the field of genetics and genomics, it aids in sequencing and annotating genomes and their observed mutations. It plays a role in the text mining of biological literature and the development of biological and gene ontologies to organize and query biological data. It also plays a role in the analysis of gene and protein expression and regulation. Bioinformatics tools aid in the comparison of genetic and genomic data and more generally in the understanding of evolutionary aspects of molecular biology. At a more integrative level, it helps to analyze and catalogue the biological pathways and networks that are an important part of systems biology. In structural biology, it aids in the simulation and modeling of DNA, RNA, proteins as well as biomolecular interactions.
Keywords: Bioinformatics, protein expression, biomolecular, genomes, mutations
Cite this Article
Rahuldeep. An overview on Bioinformatics and its Application. Research & Reviews: A Journal of Bioinformatics. 2016; 3(2): 8–14p.
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