Amalgamation of Next-Generation Sequencing for Cancer Diagnostic Research
DOI:
https://doi.org/10.37591/(rrjobi).v5i1.200Keywords:
Next-generation sequencing, cancer diagnosis, cancer researchAbstract
Next-generation sequencing (NGS) is widely used to sequence large templates of Genome, exome and transcriptome. Over traditional sequencing method it has high resolution and success rates so it is a best option to study cancer. Combination of NGS with bioinformatic tools could be promising approach in cancer research, cancer diagnosis and treatment. In this review paper we have discussed regarding present and future of DNA sequencing in cancer genomics and also challenges faced by researchers is discussed.
Keywords: Next-generation sequencing, cancer diagnosis, cancer research
Cite this Article
Mamta Rani. Amalgamation of Next-Generation Sequencing for Cancer Diagnostic Research. Research & Reviews: A Journal of Bioinformatics. 2018; 5(1): 10–13p.
References
Metzker ML. Sequencing technologies—the next generation. Nature reviews genetics. 2010 Jan;11(1):31.
Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature. 2012 Oct;490(7418):61.
Seshagiri S, Stawiski EW, Durinck S, Modrusan Z, Storm EE, Conboy CB, Chaudhuri S, Guan Y, Janakiraman V, Jaiswal BS, Guillory J. Recurrent R-spondin fusions in colon cancer. Nature. 2012 Aug;488(7413):660.
Ding L, Ley TJ, Larson DE, Miller CA, Koboldt DC, Welch JS, Ritchey JK, Young MA, Lamprecht T, McLellan MD, McMichael JF. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature. 2012 Jan;481(7382):506.
Leyten GH, Hessels D, Smit F, Jannink S, de Jong H, et al. (2015) Identification of a candidate gene panel for the early diagnosis of prostate cancer. Clin Cancer Res 21: 3061-3070.
Shen T, Pajaro-Van de Stadt SH, Yeat NC and Lin JC-H (2015) Clinical applications of next generation sequencing in cancer: from panels, to exomes, to genomes. Front. Genet. 6:215.
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