https://techjournals.stmjournals.in/index.php/RRJoBI/issue/feedResearch & Reviews: A Journal of Bioinformatics2024-02-17T11:51:09+00:00Awani Mishraawani@celnet.inOpen Journal Systems<p><strong>Research & Reviews: A Journal of Bioinformatics (RRJoBI)</strong> Bioinformatics is an interdisciplinary field involving Biology, Computer Science and Statistics. This Journal focuses on the Research, Review works and recent developments in the area of Bioinformatics, and its applications. <span>It's a triannual journal, started in 2014.</span></p><p><strong>eISSN: 2393-8722</strong></p><p><strong><strong>Journal DOI no.: <strong>10.37591/RRJoBI</strong></strong></strong></p><p><strong>Indexed in: </strong>DRJI, Citefactor, Journal TOC, Google Scholar, <a href="https://journals.indexcopernicus.com/search/form?search=Research%20%26%20Reviews:%20A%20Journal%20of%20Dentistry">Index</a><a href="https://journals.indexcopernicus.com/search/form?search=Research%20%26%20Reviews:%20A%20Journal%20of%20Bioinformatics"> Copernicus ICV: 60.22, SJIF 6.017</a></p><div> <strong>Focus and Scope Cover</strong></div><ul><li>Sequence database and Sequence Alignment</li><li>Sequence mining, Sequence profiling</li><li>System biology</li><li>Biological networks, protein-protein interaction networks</li><li>DNA Assembly, Clustering, Mapping</li><li>Phylogeny reconstruction algorithms</li><li>Protein Structure predictions</li><li>Silico technology</li><li>Statistical analysis, stochastic grammars</li></ul><p>All contributions to the journal are rigorously refereed and are selected on the basis of quality and originality of the work. The journal publishes the most significant new research papers or any other original contribution in the form of reviews and reports on new concepts in all areas pertaining to its scope and research being done in the world, thus ensuring its scientific priority and significance.</p><p><a title="Editorial Board" href="/index.php/RRJoBI/about/editorialTeam" target="_blank">EDITORIAL BOARD</a></p>https://techjournals.stmjournals.in/index.php/RRJoBI/article/view/1516"An Investigative Examination to Evaluate the Frequency and Impact of Excessive Utilization of Earphones and Audio Devices Among Young Adults in the District of Fatehgarh Sahib, Punjab”2024-02-17T11:51:09+00:00Bhupinder Kaurbhupindersandhu1092@gmail.com<p>&quot;An Investigative Examination to Evaluate the Frequency and Impact of Excessive<br />Utilization of Earphones and Audio Devices Among Young Adults in the District of<br />Fatehgarh Sahib, Punjab. Objective: To examine how widespread the excessive use of<br />earphones and music devices is among younger adults. To evaluate the impact of excessive<br />use of earphones and music devices on younger adults. To investigate the correlation between<br />the overuse of earphones and music devices and specific demographic factors among<br />individuals in the district of Fatehgarh Sahib, Punjab. The study employed an exploratory<br />research design, and the sample of 200 students was selected using a non-probability<br />purposive sampling technique. The population of present study was younger adults of<br />colleges and universities of district Fathegarh Sahib. To evaluate the frequency, manner, and<br />consequences of overusing earphones and other music devices through a self-designed<br />questionnaire. Data was collected through demographic data sheet for assessment of<br />demographic variable.<br />&quot;Factors such as age, gender, educational attainment, academic discipline, year of study,<br />religious affiliation, relationship status, residential area, and family income were considered.<br />A self-designed questionnaire was employed to evaluate the frequency and prevalence of the<br />excessive use of earphones and other music devices among young adults. A self-structured<br />checklist was used to assess the effect of earphones and also self-structured likert scale to</p><p>assess the prevalence and pattern of using earphones and other musical devices. The<br />findings indicate that among younger adults, 1.5% experienced severe hearing<br />effects, 34.0% had moderate impacts, and 64.5% exhibited mild effects.<br />Consequently, it can be inferred that the majority of younger adults encountered<br />mild effects on their hearing</p>2024-12-31T00:00:00+00:00Copyright (c) 2024 Research & Reviews: A Journal of Bioinformaticshttps://techjournals.stmjournals.in/index.php/RRJoBI/article/view/1518Role of Innovative Use of Toothbrush in Debridement of Post Burn Scalp Wound2024-02-17T11:51:09+00:00Ravi Kumar Chittoriadrchittoria@yahoo.comPradossh .drchittoria@yahoo.comAmrutha J Sdrchittoria@yahoo.comSurgical debridement is the gold standard of burn debridement and can be performed using a variety of tools. This procedure eliminates necrotic tissue and foreign debris, leading to a reduction in bacterial load and facilitating the culture of the excised skin if required. Surgical debridement, primarily conducted using surgical knives like the Weck/Goulian knife and the Blair knife, has been the conventional method for this purpose. Challenging regions for debridement include contoured areas like inter-web spaces in the hands and feet, delicate areas such as the face and dorsum of the hands, and areas prone to swelling due to fluid resuscitation. Surgical knives can sometimes result in incomplete or uneven debridement leading to multiple passes and prolonged operative time and increased bleeding. There is a lack of agreement regarding the optimal tools for wound excision and debridement, with the choice typically left to the discretion of the operating surgeon and the resources accessible at each facility. When selecting from the diverse range of techniques and instruments for burn excision, factors to weigh include the impact on quality of life, the physiology of the affected region, physical aesthetics, and overall survival, emphasizing the importance of a thoughtful and individualized approach in the decision-making process.2023-12-31T00:00:00+00:00Copyright (c) 2024 Research & Reviews: A Journal of Bioinformaticshttps://techjournals.stmjournals.in/index.php/RRJoBI/article/view/1519Use of Three Layered Regenerative Scaffold Dressing in the Wound Bed Preparation of Second Degree Scald Burns2024-02-17T11:51:09+00:00Ravi Kumar Chittoriadrchittoria@yahoo.comViswak Mdrchittoria@yahoo.comAmrutha J.S J Sdrchittoria@yahoo.comBurn injuries are prevalent among children, with thermal, scald, and electrical burns being the primary causes. Among these, scald injuries are particularly common in children under the age of five, constituting more than 65% of reported cases. In contemporary settings, diverse scaffolds are employed to enhance the healing process and minimize scar formation. Collagen serves as a crucial scaffold, facilitating tissue regeneration and promoting the formation of new blood vessels. Furthermore, alternative scaffolds such as the amniotic membrane exhibit unique anti-inflammatory and bacteriostatic properties, contributing to proper epithelization and reducing scarring. Silicone gel sheets, with their hydrophobic characteristics, play a role in minimizing scarring and providing analgesia. This study focuses on a novel approach employing a three-layered scaffold dressing for a second-degree scald burn in a pediatric patient. The multi-layered scaffold is designed to optimize the healing process and mitigate scarring. By incorporating materials like collagen, amniotic membrane, and silicone gel sheets, the dressing aims to provide a comprehensive solution that addresses the specific challenges posed by pediatric burn injuries. The utilization of such advanced scaffolds reflects ongoing efforts to improve therapeutic outcomes and enhance the overall quality of care for pediatric burn patients, emphasizing the importance of a multidimensional approach in managing these common injuries.2024-02-17T11:50:41+00:00Copyright (c) 2024 Research & Reviews: A Journal of Bioinformaticshttps://techjournals.stmjournals.in/index.php/RRJoBI/article/view/1515Exploration and Advancement of Drugs Within the Field of Bioinformatics: A Review2024-02-17T11:51:09+00:00Pramod chikkodipramodchikkodi115@gmail.comRushikesh Balu Shendagepramodchikkodi115@gmail.com<em><span>After selection, research objectives fall under the supervision of either the pharmaceutical industry or pertinent academic institutions. The initial approach involves identifying drug molecules possessing the essential qualities necessary for the synthesis of targeted medications. Drug development constitutes the subsequent phase following the discovery of a drug and unfolds as a meticulous process aimed at introducing novel pharmaceuticals to the market. This intricate journey from discovery to market availability encompasses a substantial timeframe, often spanning two decades. Along this trajectory, the drug development process demands meticulous efforts, rigorous testing, and adherence to regulatory standards. The financial investment involved in this extensive undertaking can amount to a staggering $3 billion before the developed drug is deemed fit for clinical utilization. The pharmaceutical industry and academic institutions play a pivotal role in steering the course of research targets, overseeing the intricate process of drug development. The initial step involves discerning drug molecules endowed with the requisite properties, laying the foundation for subsequent phases. As drugs progress through the intricate stages of development, including pre-clinical and clinical trials, the cumulative investment of time and financial resources becomes evident. Ultimately, this exhaustive process aims to ensure that new drugs, backed by comprehensive research and testing, meet the stringent criteria for safety, efficacy, and regulatory approval before reaching the crucial stage of clinical utilization</span></em>2023-12-31T00:00:00+00:00Copyright (c) 2024 Research & Reviews: A Journal of Bioinformaticshttps://techjournals.stmjournals.in/index.php/RRJoBI/article/view/1517A comprehensive analysis of pharmaceutical compound utilization in the context of molecular docking2024-02-17T11:51:09+00:00Rutuja Dashrath Chougulerutujachougule4548@gmail.com<p>Drug design is a longstanding and complex medical science. There have been many successes in drug development since the late 19th century, when Emil Fisher suggested that the interaction between drugs was similar to a key and a lock. Drug development has increasingly evolved into qualitative research integrated with theoretical and practical methods. Drug development is no w the best path to drug discovery. It uses the latest advances in science andtechnology and incorporates them into its extensive arsenal of methods and tools to achieve its main goal: to discover effective, unique, nontoxic, safe and effective medicine </p>2023-12-31T00:00:00+00:00Copyright (c) 2024 Research & Reviews: A Journal of Bioinformatics