A Comprehensive Analysis of Aloe Vera Gel Processing and Its Antidiabetic Properties: A 3D Computational Biology Perspective"

Authors

  • Pramod chikkodi HOD, Nootan College of Pharmacy,kavathemahankal, Sangli (MH)
  • Kengar Manohar Assist. Professor, Nootan College of Pharmacy,kavathemahankal, Sangli
  • Patil Amol Vice Principal, Nootan College of Pharmacy,kavathemahankal, Sangli (MH)

DOI:

https://doi.org/10.37591/(rrjobi).v10i2.1449

Keywords:

Aloe vera gel, Aloe vera gel expulsion extraction, filleting, leaf splitter method purification, stabilization, antidiabetic properties, hypoglycemic effects, 3D computational biology, molecular modeling, metabolic pathways, antioxidant potential.

Abstract


This expansive review paper delves into the intricate realm of Aloe vera gel processing and its potential antidiabetic properties, augmented through the lens of 3D computational biology. The review amalgamates insights from various references to elucidate the handling, harvesting, and juice extraction of Aloe vera gel. Additionally, it explores diverse products derived from Aloe vera, such as Aloe juice, Aloe health drink, and Aloe dessert, providing an extensive understanding of their preparation methods and potential applications. The paper delves into the intricate structure of Aloe vera leaves, emphasizing the physical characteristics and active components contributing to its medicinal properties.

 The prime focus of this comprehensive review revolves around the antidiabetic and hypoglycemic properties of Aloe vera, scrutinizing them from a 3D computational biology perspective. Emphasis is placed on elucidating how Aloe vera aids in lowering blood glucose levels and enhancing insulin sensitivity. Advanced computational modeling and simulations are employed to analyze the intricate interactions between Aloe vera constituents and metabolic pathways, shedding light on the molecular mechanisms underlying its antidiabetic effects. The potential role of Aloe vera's antioxidant properties in mitigating oxidative stress and diabetes is explored through sophisticated computational models, offering a deeper understanding of its therapeutic impact.

References

Haghani F, Arabnezhad MR, Mohammadi S, Ghaffarian-Bahraman A. Aloe vera and Streptozotocin-Induced Diabetes Mellitus. Rev Bras Farmacogn. 2022; 32(2):174-187.

Sánchez M, González-Burgos E, Iglesias I, Gómez-Serranillos MP. Pharmacological Update Properties of Aloe Vera and its Major Active Constituents. Molecules. 2020 Mar 13;25(6):1324.

Deora N, Venkatraman K. Aloe vera in diabetic dyslipidemia: Improving blood glucose and lipoprotein levels in pre-clinical and clinical studies. J Ayurveda Integr Med. 2022 Oct-Dec;13(4):100675.

Abid Aslam Maan, Akmal Nazir, Muhammad Kashif Iqbal Khan, Tahir Ahmad, Rabia Zia, Misbah Murid, Muhammad Abrar, The therapeutic properties and applications of Aloe vera: A review, Journal of Herbal Medicine, Volume 12, 2018, Pages 1-10.

Surjushe A, Vasani R, Saple D G. Aloe vera: A short review. Indian J Dermatol 2008;53:163-6.

Purohit SK, Solanki R , Soni MK , Mathur V. Experimental evaluation of Aloe vera leaves pulp as topical medicament on wound healing. IJPR, 2012; 2: 110-12.

Agarwal A, Dwivedi N. Aloe vera: Magic or myth . SRM J Res Dent Sci 2013;4:119-24.

Amira Mourad Hussein Abo-Youssef, Basim Anwar Shehata Messiha, Beneficial effects of Aloe vera in treatment of diabetes: Comparative in vivo and in vitro studies, Bulletin of Faculty of Pharmacy, Cairo University, 2013, 51(1):7-11.

V. K. Chandegara1, A. K. Varshney, Aloe vera L. processing and products: A review ,Int. J. Med. Arom. 2013,3(4): 2249 – 4340.

Alethia Muñiz-Ramirez , Rosa M. Perez, Efren Garcia, Fabiola E. Garcia, Antidiabetic Activity of Aloe vera Leaves, Evidence-Based Complementary and Alternative Medicine,2020, Article ID 6371201.

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Published

2023-10-22

Issue

Vol. 10 No. 2 (2023)

Section

Review Article

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