Review of Nishakathakadi—An Ayurvedic Formulation of Turmeric etc. in Diabetes

Authors

  • Gyanendra Kumar Gupta Professor & HOD, Department of Kriya Sharir, Shri Babu Singh Jay Singh Ayurvedic Medical College & Hospital, Farrukhabad, Uttar Pradesh, India
  • Gagan Devi Assistant Professor, Department of Rachna Sharir, Bharat Ayurved Medical College Hospital & Research Centre, Muzaffarnagar, Uttar Pradesh, India

DOI:

https://doi.org/10.37591/(rrjobi).v10i1.1437

Keywords:

Nishakathakadi yoga, sahasrayoga, kashaya prakaran, prameha chikitsa, and madhumeha

Abstract

The present abstract was aimed to discuss the Sahasrayoga portion on “Kashaya Prakaran,” which contains a reference to “Nishakathakadi Yoga” as a therapy for “Prameha” (diabetes). This particular combination of Tikta, Katu, and Kashaya Rasa, along with Katu Vipaka, Laghu, Ruksha, and Tikshna Guna Pradhana Aushadhi, is suggested to be effective in differentiating the etiology of “Madhumeha” (diabetes). The Nishakathakadi yoga formulation also exhibits Rasayana (rejuvenating), Deepana (digestive stimulant), and Pachana (digestive) properties. The present study was designed to further explore the extensive usage of “Nishakathakadi Yoga” in treating “Madhumeha” (diabetes) by considering all relevant factors. The aim of the present study was to provide a comprehensive understanding of the therapeutic potential of Nishakathakadi yoga in managing diabetes. The present study was aimed to elucidate the unique qualities of Nishakathakadi formulation and its relevance in diabetes treatment by examining the specific components of this formulation, such as the presence of Tikta, Katu, and Kashaya Rasa (bitter, pungent, and astringent tastes), as well as its Katu Vipaka (pungent metabolic effect) and the predominance of Laghu, Ruksha, and Tikshna Guna (light, dry, and sharp qualities). Furthermore, the present study explored the Rasayana property of Nishakathakadi yoga, which indicated its potential for rejuvenating the body and improving overall health. The Deepana and Pachana properties of Nishakathakadi formulation, which stimulate digestion and enhance metabolic processes, respectively, were also investigated to determine their role in managing diabetes. By conducting the present study, we seek to shed light on the efficacy and mechanisms of action of Nishakathakadi yoga in the context of diabetes treatment. The findings will contribute to a better understanding of traditional medicinal practices and their potential integration into contemporary healthcare approaches for managing diabetes.

References

Antony A, Raghu K. Investigation on key molecular targets responsible for antidiabetic properties of Symplocos cochinchinensis (Lour.) S. Moore. Doctor of Philosophy in Biotechnology. Cochin: Cochin University of Science & Technology; 2014. Available from: https://dyuthi.cusat.ac.in/xmlui/bitstream/handle/purl/4961/Dyuthi-T2037.pdf?sequence=1 (cited on 2023 Jul 18).

Srikanth N, Haripriya N, Singh R, Tewari D. Diabetes mellitus (madhumeha) and ayurvedic management: an evidence based approach [Internet]. World Journal of Pharmacy and Pharmaceutical Sciences. 2015; 4(8): 881–892p. Available from: https://www.researchgate.net/publication/280610018_diabetes_mellitus_madhumeha_and_ayurvedic_management_an_evidence_based_approach [cited on 2023 Jul 18].

Gupta V, Keshari BB, Tiwari SK, Murthy KHHVSSN. A comparative study of Shilajatu and Asanadi Ghana Vati in the management of Madhumeha w.s.r. to type-2 diabetes mellitus. Ayu. 2016; 37(2): 120–124p. doi: 10.4103/ayu. AYU_211_15. PMID: 29200750; PMCID: PMC5688834.

Munishwar N, Sushil Vilas C, Suraj R, Scholar P. A case study on the relation between madhumeha wsrt diabetes mellitus (type ii) and aamvata wsrt rheumatoid arthritis and its management. International Ayurvedic Medical Journal [Internet]; 2016. Available from: http://www.iamj.in/posts/images/upload/2660_2664_1.pdf [cited on 2023 Jul 18].

Antu KA, Riya MP, Nair A, Mishra A, Srivastava AK, Raghu KG. Symplocos cochinchinensis enhances insulin sensitivity via the down regulation of lipogenesis and insulin resistance in high energy diet rat model. J Ethnopharmacol. 2016; 193: 500–509p. doi: 10.1016/j.jep.2016.09.050. Epub 2016 Sep 27. PMID: 27686268.

Nariyal V, Sharma P, Saroj U. A criticle review on avaranajanyamadhumeha with special reference to diabetes mellitus type II. International Ayurvedic Medical Journal. 2016; 1(1): 96–100p. Available from: http://www.iamj.in/prposts/2016/images/upload/96_100.pdf [cited on 2023 Jul 18].

Talekar M, Sevatkar BK, Deshmukh PN, Reddy GR. An epidemiological study to find out santarpanottha hetu in patients of madhumeha (diabetes mellitus) AT. International Journal of Research in Ayurveda and Pharmacy. 2017; 8(5): 185–190p. Available from: https://www.researchgate.net/publication/320391539_an_epidemiological_study_to_find_out_santarpanottha_hetu_in_patients_of_madhumeha_diabetes_mellitus_at_jaipur_and_its_periphery [cited 2023 Jul 18].

Angelie S, Rao M, Anthony J, Prabhu K, Kavimani M, Balasubramanian BS, Sundaram RL, Dinakar S. Antioxidant Study of One Ayurvedic Preparation Katakakhadiradi Kashayam. J Phar Sci & Res. 2017; 9(9): 1427–1429p. Available from: https://www.jpsr.pharmainfo.in/ Documents/Volumes/vol9Issue09/jpsr09091705.pdf [cited on 2023 Jul 18].

Arya M, Mishra D. Clinical Evaluation of the effect of Divya Madhushini vati and Phaltrikadi kwaath in Madhumeha. World Journal of Pharmaceutical Research. 2015; 7(8): 462–467p. Available from: https://wjpr.net/abstract_show/9851 [cited 2023 Jul 18]

Nigam P, Dwivedi OP, Jain JC, Khuje S. Role of Basti Karma towards the management of Madhumeha: An Ayurveda perspective. Journal of Drug Delivery & Therapeutics. 2018; 8(6-s): 400–406p. Available from: https://jddtonline.info/index.php/jddt/article/view/2143 [cited on 2023 Jul 18]. 11. Gilani AH, Shaheen F, Zaman M, Janbaz KH, Shah BH, Akhtar MS. Studies on antihypertensive and antispasmodic activities of methanol extract of Acacia nilotica pods. Phytotherapy Research. 1999; 13 (8): 665–669p. Available from: https://www.feedipedia.org/node/14980 [cited on 2023 Jul 18].

Downloads

Published

2023-09-08

Issue

Vol. 10 No. 1 (2023)

Section

Research Article

License

Declaration and Copyright Transfer Form

(to be completed by authors)

I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.

  • I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
  • I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
  • I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
  •  I/We also agree to the authorship of the article in the following order:

Author’s name                                    

 

1. ________________

2. ________________

3. ________________

4. ________________

 

We  Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal.