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Genetics of Bipolar Disorder: A Review

Kirtana Mehta, Anjali Kulkarni, Yachana Jha


Bipolar disorder is a complex psychiatric condition that is thought to have a significant genetic component. This article explores the genetic basis of bipolar disorder, including the potential genetic risk factors and the biological mechanisms that contribute to the development of this disorder. The article discusses the various genetic studies that have been conducted to identify genes and genetic variants associated with bipolar disorder, including genome-wide association studies (GWAS) and candidate gene studies. The article concludes with a discussion of the implications of genetic research for the diagnosis, treatment and prevention of bipolar disorder. Overall, this article provides a comprehensive overview of the genetic basis of bipolar disorder and highlights the importance of continued research in this area to improve our understanding and management of this complex condition.


Bipolar disorder, neuroinflammation, psychosis, depression, biological markers, cytokines, substance use disorder, anxiety

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