Evaluation of Biomedical Importance of Papaya Pulp

Abstract

The present study describes the preparation of petroleum ether, ethyl acetate, and methanol extract from Carica papaya; further the extracts revealed dose dependent anti-oxidant potential. Among the extracts, ethyl acetate extract showed more percentage of scavenging than other two extracts. The screening of antimicrobial activity for three extracts revealed antimicrobial potency towards 12 test organisms. Among these extracts, petroleum ether shows more activity against 12 microbes compared with other two extracts. The petroleum ether extract showed the presence of alkaloids, coumarin, sugars, terpenoids, flavonoids, protein glycosides and carboxylic acid. This result is same in ethyl acetate and methanol extract. All three extracts when screened showed marginal anti-cancer activity against breast cancer cell line (MCF7). Thus the present investigation revealed that Carica papaya holds potent anti-oxidant, antimicrobial, phytochemical constituents and marginal anti-cancer activity.

Keywords: Antimicrobial activity, Carica papaya, phytochemical analysis, scavenging activity

Cite this Article V. Balamurugan, J. Ramamoorthy, A. Sabaridasan. Evaluation of Biomedical Importance of Papaya Pulp. Research & Reviews: A Journal of Biotechnology. 2017; 7(3): 14–19p.